8SDF
Crystal structure of SARS-CoV-2 receptor binding domain in complex with neutralizing antibody CC25.4
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | Z, A | Spike protein S1 | polymer | 205 | 23104.9 | 2 | UniProt (P0DTC2) Pfam (PF09408) In PDB | Severe acute respiratory syndrome coronavirus 2 | |
2 | H, B | Neutralizing antibody CC25.4 heavy chain | polymer | 229 | 25114.2 | 2 | Homo sapiens (human) | ||
3 | L, C | Neutralizing antibody CC25.4 light chain | polymer | 217 | 22815.1 | 2 | Homo sapiens (human) | ||
4 | D | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 570.5 | 1 | In PDB GlyTouCan (G21290RB) | |||
5 | Z, H, L, A, B... | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 8 | Chemie (MPD) | |||
6 | A | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 1 | Chemie (NAG) | |||
7 | water | water | 18.0 | 780 | Chemie (HOH) |
Sequence modifications
Z, A: 333 - 530 (UniProt: P0DTC2)
PDB | External Database | Details |
---|---|---|
Gly 531 | - | expression tag |
His 532 | - | expression tag |
His 533 | - | expression tag |
His 534 | - | expression tag |
His 535 | - | expression tag |
His 536 | - | expression tag |
His 537 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 142068.2 | |
Branched | Number of molecules | 1 |
Total formula weight | 570.5 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 1166.6 | |
All* | Total formula weight | 143805.3 |