Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

8SCB

Terminating ribosome with SRI-41315

This is a non-PDB format compatible entry.

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Ribosomal protein L8	polymer	257	28088.9	1	UniProt (G1TT27) Pfam (PF00181) Pfam (PF03947)	Oryctolagus cuniculus (rabbit)
2	B (B)	Ribosomal protein L3	polymer	403	46108.0	1	UniProt (G1TL06) Pfam (PF00297)	Oryctolagus cuniculus (rabbit)
3	C (C)	60S ribosomal protein L4	polymer	413	46388.9	1	UniProt (G1SVW5) Pfam (PF00573) Pfam (PF14374)	Oryctolagus cuniculus (rabbit)
4	D (D)	Ribosomal_L18_c domain-containing protein	polymer	297	34481.8	1	UniProt (G1SYJ6) UniProt (by SIFTS) (P19949)	Oryctolagus cuniculus (rabbit)
5	E (E)	60S ribosomal protein L6	polymer	291	33028.3	1	UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159)	Oryctolagus cuniculus (rabbit)
6	F (F)	60S ribosomal protein L7	polymer	247	29201.8	1	UniProt (G1TUB1) Pfam (PF08079) Pfam (PF00327)	Oryctolagus cuniculus (rabbit)
7	G (G)	60S ribosomal protein L7a	polymer	319	36221.5	1	UniProt (G1STW0) Pfam (PF01248)	Oryctolagus cuniculus (rabbit)
8	H (H)	60S ribosomal protein L9	polymer	192	21871.4	1	UniProt (G1SWI6) Pfam (PF00347)	Oryctolagus cuniculus (rabbit)
9	I (I)	60S ribosomal protein L10	polymer	214	24643.1	1	UniProt (B7NZQ2) Pfam (PF00252)	Oryctolagus cuniculus (rabbit)
10	J (J)	60S ribosomal protein L11	polymer	178	20288.5	1	UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673)	Oryctolagus cuniculus (rabbit)
11	K (L)	eL13	polymer	211	24331.7	1		Oryctolagus cuniculus (rabbit)
12	L (M)	60S ribosomal protein L14	polymer	218	23870.5	1	UniProt (G1SZ12) Pfam (PF01929)	Oryctolagus cuniculus (rabbit)
13	M (N)	Ribosomal protein L15	polymer	204	24207.3	1	UniProt (G1T0C1) Pfam (PF00827)	Oryctolagus cuniculus (rabbit)
14	N (O)	uL13	polymer	203	23533.3	1		Oryctolagus cuniculus (rabbit)
15	O (P)	uL22	polymer	184	21444.2	1	UniProt (G1TVT6) Pfam (PF00237) UniProt (by SIFTS) (G1SCJ6)	Oryctolagus cuniculus (rabbit)
16	P (Q)	Ribosomal protein L18	polymer	188	21699.7	1	UniProt (G1TFE0) Pfam (PF17135)	Oryctolagus cuniculus (rabbit)
17	Q (R)	Ribosomal protein L19	polymer	196	23535.3	1	UniProt (G1TJR3) Pfam (PF01280)	Oryctolagus cuniculus (rabbit)
18	R (S)	eL20	polymer	176	20827.6	1		Oryctolagus cuniculus (rabbit)
19	S (T)	eL21	polymer	160	18610.0	1	UniProt (G1SHQ2) Pfam (PF01157)	Oryctolagus cuniculus (rabbit)
20	T (U)	eL22	polymer	128	14813.0	1	UniProt (G1TSG1) Pfam (PF01776)	Oryctolagus cuniculus (rabbit)
21	U (V)	Ribosomal protein L23	polymer	140	14892.5	1	UniProt (G1T6D1) Pfam (PF00238)	Oryctolagus cuniculus (rabbit)
22	V (W)	60S ribosomal protein L24	polymer	157	17825.1	1	UniProt (G1SE28) Pfam (PF01246)	Oryctolagus cuniculus (rabbit)
23	W (X)	eL23	polymer	156	17768.2	1	UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276)	Oryctolagus cuniculus (rabbit)
24	X (Y)	uL24	polymer	145	17303.4	1	UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467)	Oryctolagus cuniculus (rabbit)
25	Y (Z)	60S ribosomal protein L27	polymer	136	15835.8	1	UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777)	Oryctolagus cuniculus (rabbit)
26	Z (a)	60S ribosomal protein L27a	polymer	148	16620.6	1	UniProt (G1SNY0) Pfam (PF00828)	Oryctolagus cuniculus (rabbit)
27	AA (b)	60S ribosomal protein L29	polymer	245	26708.7	1	UniProt (G1SGR6) Pfam (PF01779)	Oryctolagus cuniculus (rabbit)
28	BA (c)	eL30	polymer	115	12807.1	1	UniProt (G1TDL2) Pfam (PF01248)	Oryctolagus cuniculus (rabbit)
29	CA (d)	eL31	polymer	125	14494.9	1	UniProt (G1SHG0) Pfam (PF01198)	Oryctolagus cuniculus (rabbit)
30	DA (e)	eL32	polymer	135	15898.9	1	UniProt (G1U437) Pfam (PF01655) UniProt (by SIFTS) (G1TUN8)	Oryctolagus cuniculus (rabbit)
31	EA (f)	eL33	polymer	110	12580.8	1	UniProt (G1SF08) Pfam (PF01247)	Oryctolagus cuniculus (rabbit)
32	FA (g)	60S ribosomal protein L34	polymer	117	13326.1	1	UniProt (G1TXG5) Pfam (PF01199)	Oryctolagus cuniculus (rabbit)
33	GA (h)	eL35	polymer	123	14566.6	1	UniProt (G1SIT5) Pfam (PF00831)	Oryctolagus cuniculus (rabbit)
34	HA (i)	60S ribosomal protein L36	polymer	105	12263.8	1	UniProt (G1TTQ5) Pfam (PF01158)	Oryctolagus cuniculus (rabbit)
35	IA (j)	Ribosomal protein L37	polymer	97	11111.0	1	UniProt (U3KPD5) Pfam (PF01907)	Oryctolagus cuniculus (rabbit)
36	JA (k)	60S ribosomal protein L38	polymer	70	8238.9	1	UniProt (G1U001) Pfam (PF01781)	Oryctolagus cuniculus (rabbit)
37	KA (l)	eL39	polymer	51	6455.8	1	UniProt (G1TTN1) Pfam (PF00832)	Oryctolagus cuniculus (rabbit)
38	LA (m)	Ubiquitin A-52 residue ribosomal protein fusion product 1	polymer	93	10865.9	1	UniProt (A0A2K5PSA0) Pfam (PF00240) Pfam (PF01020)	Oryctolagus cuniculus (rabbit)	Ubiquitin-60S ribosomal protein L40
39	MA (n)	eL41	polymer	25	3473.5	1	UniProt (A0A087WNH4) Pfam (PF05162)	Oryctolagus cuniculus (rabbit)	60s ribosomal protein l41
40	NA (o)	eL42	polymer	106	12477.0	1	UniProt (G1U344) Pfam (PF00935) UniProt (by SIFTS) (G1T040)	Oryctolagus cuniculus (rabbit)
41	OA (p)	eL43	polymer	92	10299.4	1	UniProt (G1SY53) Pfam (PF01780)	Oryctolagus cuniculus (rabbit)
42	PA (r)	eL28	polymer	137	15783.6	1	UniProt (G1U7L1) Pfam (PF01778)	Oryctolagus cuniculus (rabbit)
43	QA (s)	60S acidic ribosomal protein P0	polymer	318	34380.5	1	UniProt (G1SPK4) Pfam (PF00466) Pfam (PF17777) Pfam (PF00428)	Oryctolagus cuniculus (rabbit)
44	RA (t)	60S ribosomal protein L12	polymer	165	17847.6	1	UniProt (G1SMR7) Pfam (PF03946) Pfam (PF00298)	Oryctolagus cuniculus (rabbit)
45	SA (1)	NC	polymer	130	13964.3	1		Homo sapiens
46	TA (2)	P_tRNA	polymer	76	24436.6	1		Oryctolagus cuniculus (rabbit)
47	UA (3)	E_tRNA	polymer	75	24102.3	1		Oryctolagus cuniculus (rabbit)
48	VA (5)	28S_rRNA	polymer	3543	1149054.1	1		Oryctolagus cuniculus (rabbit)
49	WA (7)	5S_rRNA	polymer	120	38691.9	1	GenBank (X06789.1)	Oryctolagus cuniculus (rabbit)
50	XA (8)	5.8S_rRNA	polymer	156	50157.7	1		Oryctolagus cuniculus (rabbit)
51	YA (9)	18S_rRNA	polymer	1869	603440.9	1		Oryctolagus cuniculus (rabbit)
52	ZA (AA)	uS2 (SA)	polymer	295	32928.0	1	UniProt (G1TLT8) Pfam (PF00318) Pfam (PF16122)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein SA, 37 kDa laminin receptor precursor,37LRP,37/67 kDa laminin receptor,LRP/LR,67 kDa laminin receptor,67LR,Laminin receptor 1,LamR,Laminin-binding protein precursor p40,LBP/p40
53	AB (BB)	eS1	polymer	264	30002.1	1	UniProt (G1SS70) Pfam (PF01015)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S3a
54	BB (CC)	uS5	polymer	293	31327.4	1		Oryctolagus cuniculus (rabbit)
55	CB (DD)	Ribosomal protein S3	polymer	243	26715.3	1	UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189)	Oryctolagus cuniculus (rabbit)
56	DB (EE)	eS4 (S4 X isoform)	polymer	263	29654.9	1	UniProt (G1TK17) Pfam (PF08071) Pfam (PF00900) Pfam (PF00467) Pfam (PF16121)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S4
57	EB (FF)	uS7	polymer	204	22913.5	1	UniProt (G1TFM5) Pfam (PF00177)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S5
58	FB (GG)	eS6	polymer	249	28751.9	1	UniProt (G1TM55) Pfam (PF01092)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S6
59	GB (HH)	eS7	polymer	194	22168.9	1	UniProt (G1SVB0)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S7
60	HB (II)	eS8	polymer	208	24263.4	1	UniProt (G1TJW1) Pfam (PF01201)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S8
61	IB (JJ)	uS4	polymer	194	22641.6	1	UniProt (B7NZS8) Pfam (PF00163) Pfam (PF01479)	Oryctolagus cuniculus (rabbit)	Ribosomal protein S9
62	JB (KK)	S10_plectin domain-containing protein	polymer	165	18933.8	1	UniProt (G1TPV3) Pfam (PF03501)	Oryctolagus cuniculus (rabbit)
63	KB (LL)	uS17	polymer	158	18468.8	1	UniProt (G1TRM4) Pfam (PF16205) Pfam (PF00366)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S11
64	LB (MM)	eS12	polymer	132	14539.0	1	UniProt (G1SFR8) Pfam (PF01248)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S12
65	MB (NN)	uS15	polymer	151	17259.4	1	UniProt (G1SP51) Pfam (PF08069) Pfam (PF00312)	Oryctolagus cuniculus (rabbit)	Ribosomal protein S13
66	NB (OO)	uS11	polymer	168	18134.0	1	UniProt (G1U472) Pfam (PF00411) UniProt (by SIFTS) (G1T1F0)	Oryctolagus cuniculus (rabbit)
67	OB (PP)	uS19	polymer	145	17049.2	1	UniProt (G1U0Q2) Pfam (PF00203)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S15
68	PB (QQ)	uS9	polymer	146	16477.4	1	UniProt (G1SGX4) Pfam (PF00380)	Oryctolagus cuniculus (rabbit)
69	QB (RR)	eS17	polymer	135	15552.1	1	UniProt (G1TU13) Pfam (PF00833)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S17
70	RB (SS)	uS13	polymer	152	17759.8	1	UniProt (G1TPG3) Pfam (PF00416)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S18
71	SB (TT)	eS19	polymer	145	16106.6	1	UniProt (G1TN62) Pfam (PF01090)	Oryctolagus cuniculus (rabbit)
72	TB (UU)	uS10	polymer	119	13398.8	1	UniProt (G1SIZ2) Pfam (PF00338)	Oryctolagus cuniculus (rabbit)
73	UB (VV)	eS21	polymer	83	9124.4	1	UniProt (G1TM82) Pfam (PF01249)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S21
74	VB (WW)	uS8	polymer	130	14865.6	1	UniProt (G1TG89) Pfam (PF00410)	Oryctolagus cuniculus (rabbit)	40S Ribosomal protein S15a
75	WB (XX)	uS12	polymer	143	15844.7	1	UniProt (G1SZ47) Pfam (PF00164)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S23
76	XB (YY)	40S ribosomal protein S24	polymer	130	15107.9	1	UniProt (G1T3D8) Pfam (PF01282)	Oryctolagus cuniculus (rabbit)
77	YB (ZZ)	eS25	polymer	125	13776.2	1	UniProt (G1TDB3) Pfam (PF03297)	Oryctolagus cuniculus (rabbit)
78	ZB (aa)	40S ribosomal protein S26	polymer	115	13047.5	1	UniProt (G1TFE8) Pfam (PF01283)	Oryctolagus cuniculus (rabbit)
79	AC (bb)	eS27	polymer	84	9480.2	1	UniProt (G1TZ76) Pfam (PF01667)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S27
80	BC (cc)	eS28	polymer	69	7855.1	1	UniProt (G1TIB4) Pfam (PF01200)	Oryctolagus cuniculus (rabbit)	40S Ribosomal protein S28
81	CC (dd)	uS14	polymer	56	6690.8	1	UniProt (G1U7M4) Pfam (PF00253)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S29
82	DC (ee)	eS30	polymer	133	14498.9	1	UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758)	Oryctolagus cuniculus (rabbit)	40S ribosomal protein S30
83	EC (ff)	eS31	polymer	156	18004.0	1	UniProt (G1SK22) Pfam (PF00240) Pfam (PF01599)	Oryctolagus cuniculus (rabbit)	Ribosomal protein S27a
84	FC (gg)	Receptor for Activated C Kinase 1 (RACK1)	polymer	317	35115.7	1	UniProt (G1SJB4) Pfam (PF00400)	Oryctolagus cuniculus (rabbit)
85	GC (hh)	mRNA	polymer	197	63720.9	1		Homo sapiens
86	HC (ii)	Eukaryotic peptide chain release factor subunit 1	polymer	459	51667.6	1	UniProt (P62495) Pfam (PF03463) Pfam (PF03464) Pfam (PF03465)	Homo sapiens (human)	Eukaryotic release factor 1,eRF1,Protein Cl1,TB3-1
87	IC (jj)	ATP binding cassette subfamily E member 1	polymer	599	67405.2	1	UniProt (G1SG72) Pfam (PF04068) Pfam (PF00037) Pfam (PF00005)	Oryctolagus cuniculus (rabbit)
88	AD, AE, AF, AG, AH... (2, 5, 9, A, EE...)	MAGNESIUM ION	non-polymer		24.3	312	Chemie (MG)
89	NO, OO, PO, TC, VC... (aa, dd, ff, g, j...)	ZINC ION	non-polymer		65.4	8	Chemie (ZN)
90	RO (ii)	(2S,4aS)-2-cyclobutyl-10-methyl-3-phenyl-2,10-dihydropyrimido[4,5-b]quinoline-4,5(3H,4aH)-dione	non-polymer		359.4	1	Chemie (ZVM)
91	SO, TO (jj)	IRON/SULFUR CLUSTER	non-polymer		351.6	2	Chemie (SF4)
92	AP, BP, CP, DP, EP... (N, Q, R, V, X...)	water	water		18.0	958	Chemie (HOH)

Sequence modifications

F: 1 - 247 (UniProt: G1TUB1)

PDB	External Database	Details
Arg 61	Gly 61	conflict
Arg 93	Gly 93	conflict
Met 131	Val 131	conflict
Ile 153	Val 153	conflict

G: -52 - 266 (UniProt: G1STW0)

PDB	External Database	Details
Gly 191	Cys 244	conflict

Q: 1 - 188 (UniProt: G1TFE0)

PDB	External Database	Details
Asp 4	Asn 4	conflict
Arg 14	Trp 14	conflict
Met 53	Leu 53	conflict
Arg 58	Trp 58	conflict
Arg 75	Gln 75	conflict
Ala 80	Pro 80	conflict
Val 86	Ile 86	conflict
Arg 104	His 104	conflict
Arg 110	Cys 110	conflict
Val 137	Gly 137	conflict
Gly 157	Arg 157	conflict
Arg 181	Trp 181	conflict

R: 1 - 196 (UniProt: G1TJR3)

PDB	External Database	Details
Arg 38	Cys 38	conflict
Arg 64	Gln 64	conflict
Thr 94	Lys 94	conflict

U: 1 - 128 (UniProt: G1TSG1)

PDB	External Database	Details
Leu 18	Val 18	conflict
Gly 32	Arg 32	conflict
Ala 36	Glu 36	conflict
Phe 39	Ser 39	conflict
Gly 54	Arg 54	conflict
Val 60	Ala 60	conflict
Ser 62	Thr 62	conflict
Leu 63	Ile 63	conflict
Arg 97	His 97	conflict
Thr 106	Ser 106	conflict
Glu 126	Asp 126	conflict

k: 1 - 70 (UniProt: G1U001)

PDB	External Database	Details
Lys 24	Asn 24	conflict

7: 1 - 120 (GenBank: X06789.1)

PDB	External Database	Details
U 2	N 2	conflict
C 36	N 36	conflict
U 102	N 102	conflict
U 112	N 112	conflict
U 114	N 114	conflict
U 119	C 119	conflict
U 120	N 120	conflict

EE: 1 - 263 (UniProt: G1TK17)

PDB	External Database	Details
Gly 25	Ser 25	conflict
Arg 51	Lys 51	conflict
Thr 78	Ala 78	conflict
Val 156	Met 156	conflict

II: 1 - 208 (UniProt: G1TJW1)

PDB	External Database	Details
Arg 47	Gly 47	conflict

TT: 1 - 145 (UniProt: G1TN62)

PDB	External Database	Details
Gly 119	Trp 119	conflict

VV: 1 - 83 (UniProt: G1TM82)

PDB	External Database	Details
Asn 3	Ser 3	conflict
Asp 4	Asn 4	conflict
Gln 33	Pro 33	conflict
Phe 50	Ser 50	conflict
Ala 75	Ser 75	conflict
Asp 76	His 76	conflict
Lys 81	Gln 81	conflict

aa: 1 - 115 (UniProt: G1TFE8)

PDB	External Database	Details
Arg 28	Cys 28	conflict
Ala 56	Val 56	conflict
Arg 109	Pro 109	conflict

ii: 1 - 437 (UniProt: P62495)

PDB	External Database	Details
Met -21	-	expression tag
Arg -20	-	expression tag
Gly -19	-	expression tag
Ser -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
Gly -11	-	expression tag
Met -10	-	expression tag
Ala -9	-	expression tag
Ser -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Ala 183	Gly 183	conflict
Ala 184	Gly 184	conflict

Sequence viewer

Contents of the asymmetric unit

Polymers	Number of chains	87
Polymers	Total formula weight	3606118.7
Non-Polymers*	Number of molecules	323
Non-Polymers*	Total formula weight	9169.1
All*	Total formula weight	3615287.8

*Water molecules are not included.

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)