8S91
Structure of Walker B mutated MCM8/9 heterohexamer complex with ADP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | DNA helicase MCM8 | polymer | 840 | 93817.7 | 3 | UniProt (Q9UJA3) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | Minichromosome maintenance 8 |
| 2 | D, E, F (D, E, F) | DNA helicase MCM9 | polymer | 1143 | 127485.6 | 3 | UniProt (Q9NXL9) Pfam (PF17207) Pfam (PF00493) Pfam (PF17855) | Homo sapiens (human) | hMCM9,Mini-chromosome maintenance deficient domain-containing protein 1,Minichromosome maintenance 9 |
| 3 | G, I, K, M, O... (A, B, C, D, E...) | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 6 | Chemie (ADP) | |||
| 4 | H, J, L, N, P... (A, B, C, D, E...) | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) |
Sequence modifications
A, B, C: 1 - 840 (UniProt: Q9UJA3)
D, E, F: 1 - 1143 (UniProt: Q9NXL9)
| PDB | External Database | Details |
|---|---|---|
| Gln 519 | Glu 519 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Gln 415 | Glu 415 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 663909.9 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 2709.0 | |
| All* | Total formula weight | 666618.9 |
