8S8Z
Cryo-EM structure of octameric human CALHM1 (I109W) in complex with ruthenium red
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, A, C, D, E... | Calcium homeostasis modulator protein 1 | polymer | 314 | 34842.5 | 8 | UniProt (Q8IU99) Pfam (PF14798) In PDB | Homo sapiens (human) | Protein FAM26C |
2 | B, A, C, D, E... | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate | non-polymer | 760.1 | 8 | Chemie (POV) | |||
3 | A | ruthenium(6+) azanide pentaamino(oxido)ruthenium (1/4/2) | non-polymer | 559.5 | 1 | Chemie (R2R) |
Sequence modifications
B, A, C, D, E, F, G, H: 1 - 303 (UniProt: Q8IU99)
PDB | External Database | Details |
---|---|---|
Pro 86 | Leu 86 | conflict |
Trp 109 | Ile 109 | engineered mutation |
Asn 264 | His 264 | conflict |
Gly 304 | - | expression tag |
Ser 305 | - | expression tag |
Ala 306 | - | expression tag |
Trp 307 | - | expression tag |
Ser 308 | - | expression tag |
His 309 | - | expression tag |
Pro 310 | - | expression tag |
Gln 311 | - | expression tag |
Phe 312 | - | expression tag |
Glu 313 | - | expression tag |
Lys 314 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 8 |
Total formula weight | 278740.3 | |
Non-Polymers* | Number of molecules | 9 |
Total formula weight | 6640.1 | |
All* | Total formula weight | 285380.4 |