8S4F
Human carbonic anhydrase I covalently bound to AV21-08
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Carbonic anhydrase 1 | polymer | 260 | 28835.1 | 2 | UniProt (P00915) Pfam (PF00194) | Homo sapiens (human) | Carbonate dehydratase I,Carbonic anhydrase B,CAB,Carbonic anhydrase I,CA-I,Cyanamide hydratase CA1 |
| 2 | C, K (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D (A) | PROPANOIC ACID | non-polymer | 74.1 | 1 | Chemie (PPI) | |||
| 4 | E (A) | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 122.1 | 1 | Chemie (TRS) | |||
| 5 | F (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 6 | G, H, I, L, M (A, B) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
| 7 | J, N (A, B) | 3-(cyclooctylamino)-4-ethylsulfonyl-2,5,6-tris(fluoranyl)benzenesulfonamide | non-polymer | 428.5 | 2 | Chemie (VV8) | |||
| 8 | O (B) | ACETIC ACID | non-polymer | 60.1 | 1 | Chemie (ACY) | |||
| 9 | P, Q (A, B) | water | water | 18.0 | 497 | Chemie (HOH) |
Sequence modifications
A, B: 2 - 260 (UniProt: P00915)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 57670.2 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1632.5 | |
| All* | Total formula weight | 59302.8 |
