8S31
Crystal structure of human PLK1 Polo-Box Domain in complex with Mis18BP1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Serine/threonine-protein kinase PLK1 | polymer | 242 | 27877.8 | 2 | UniProt (P53350) Pfam (PF00659) | Homo sapiens (human) | Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13 |
| 2 | C, D (C, D) | Mis18-binding protein 1 | polymer | 11 | 1392.5 | 2 | UniProt (Q6P0N0) | Homo sapiens | Kinetochore-associated protein KNL-2 homolog,HsKNL-2,P243 |
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 211 | Chemie (HOH) |
Sequence modifications
A, B: 365 - 603 (UniProt: P53350)
| PDB | External Database | Details |
|---|---|---|
| Arg 362 | - | expression tag |
| Ser 363 | - | expression tag |
| Met 364 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 58540.6 | |
| All* | Total formula weight | 58540.6 |
