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8S30

Crystal structure of human PLK1 Polo-Box Domain in complex with Mis18

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Serine/threonine-protein kinase PLK1polymer24227877.81UniProt (P53350)
Pfam (PF00659)
Homo sapiens (human)Polo-like kinase 1,PLK-1,Serine/threonine-protein kinase 13,STPK13
2B
(B)
Protein Mis18-alphapolymer7878.91UniProt (Q9NYP9)Homo sapiensFAPP1-associated protein 1
3C, D
(A, B)
waterwater18.085Chemie (HOH)
Sequence modifications
A: 365 - 603 (UniProt: P53350)
PDBExternal DatabaseDetails
Arg 362-expression tag
Ser 363-expression tag
Met 364-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight28756.7
All*Total formula weight28756.7
*Water molecules are not included.

237735

PDB entries from 2025-06-18

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