8RWZ
Open non-crosslinked structure Brd4BD2-MZ1-(NEDD8)-CRL2VHL
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Bromodomain-containing protein 4 | polymer | 128 | 14842.1 | 1 | UniProt (O60885) Pfam (PF00439) In PDB | Homo sapiens (human) | Protein HUNK1 |
| 2 | B | von Hippel-Lindau disease tumor suppressor | polymer | 160 | 18558.2 | 1 | UniProt (P40337) Pfam (PF01847) Pfam (PF17211) In PDB | Homo sapiens (human) | Protein G7,pVHL |
| 3 | C | Elongin-B | polymer | 104 | 11748.4 | 1 | UniProt (Q15370) Pfam (PF00240) In PDB | Homo sapiens (human) | EloB,Elongin 18 kDa subunit,RNA polymerase II transcription factor SIII subunit B,SIII p18,Transcription elongation factor B polypeptide 2 |
| 4 | D | Elongin-C | polymer | 97 | 10914.5 | 1 | UniProt (L7N190) Pfam (PF03931) In PDB | Homo sapiens (human) | |
| 5 | E | Cullin-2 | polymer | 745 | 87098.9 | 1 | UniProt (Q13617) Pfam (PF00888) Pfam (PF10557) In PDB | Homo sapiens (human) | CUL-2 |
| 6 | R | Rbx1 | polymer | 199 | 22707.7 | 1 | Homo sapiens | ||
| 7 | A | (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide | non-polymer | 1004.7 | 1 | Chemie (759) | |||
| 8 | R | ZINC ION | non-polymer | 65.4 | 3 | Chemie (ZN) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 165869.8 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 1200.9 | |
| All* | Total formula weight | 167070.7 |
