8RU3
Crystal structure of beta-catenin in complex with alpha-helical peptide inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Catenin beta-1 | polymer | 534 | 58236.4 | 1 | UniProt (P35222) Pfam (PF00514) | Homo sapiens (human) | Beta-catenin |
| 2 | B (P) | Axin-1 | polymer | 14 | 1550.7 | 1 | UniProt (O15169) Pfam (PF08833) | Homo sapiens | Axis inhibition protein 1,hAxin |
| 3 | C, D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 4 | F, G (A, P) | water | water | 18.0 | 125 | Chemie (HOH) |
Sequence modifications
A: 134 - 665 (UniProt: P35222)
P: 470 - 481 (UniProt: O15169)
| PDB | External Database | Details |
|---|---|---|
| Gly 132 | - | expression tag |
| Pro 133 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ace 469 | - | acetylation |
| Leu 477 | Val 475 | engineered mutation |
| Trp 481 | Leu 479 | engineered mutation |
| Nh2 482 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 59787.2 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 106.4 | |
| All* | Total formula weight | 59893.5 |
