8RTZ
The structure of E. coli penicillin binding protein 3 (PBP3) in complex with a bicyclic peptide inhibitor
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (AAA) | Peptidoglycan D,D-transpeptidase FtsI | polymer | 348 | 37129.4 | 1 | UniProt (P0AD68) Pfam (PF00905) | Escherichia coli | Essential cell division protein FtsI,Murein transpeptidase,Penicillin-binding protein 3,PBP-3,Peptidoglycan synthase FtsI |
| 2 | B (A) | Bicyclic peptide inhibitor | polymer | 15 | 1496.8 | 1 | synthetic construct | ||
| 3 | C (A) | 1,1',1''-(1,3,5-triazinane-1,3,5-triyl)tripropan-1-one | non-polymer | 255.3 | 1 | Chemie (29N) | |||
| 4 | D, E (AAA, A) | water | water | 18.0 | 263 | Chemie (HOH) |
Sequence modifications
AAA: 234 - 279 (UniProt: P0AD68)
AAA: 295 - 588 (UniProt: P0AD68)
| PDB | External Database | Details |
|---|---|---|
| Gly 227 | - | expression tag |
| Pro 228 | - | expression tag |
| Gly 229 | - | expression tag |
| Tyr 230 | - | expression tag |
| Gln 231 | - | expression tag |
| Asp 232 | - | expression tag |
| Pro 233 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly 280 | - | linker |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 38626.2 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 255.3 | |
| All* | Total formula weight | 38881.5 |
