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8RSM

Crystal structure of Streptococcus pyogenes macrodomain in complex with ADP-ribose

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Protein-ADP-ribose hydrolasepolymer27430424.71UniProt (Q99ZI6)
UniProt (by SIFTS) (P0DN70)
Streptococcus pyogenesSpyMacroD
2B
(A)
ZINC IONnon-polymer65.41Chemie (ZN)
3C
(A)
[(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATEnon-polymer559.31Chemie (AR6)
4D
(A)
waterwater18.0127Chemie (HOH)
Sequence modifications
A: 1 - 270 (UniProt: Q99ZI6)
PDBExternal DatabaseDetails
Gly -3-expression tag
Pro -2-expression tag
Met -1-expression tag
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight30424.7
Non-Polymers*Number of molecules2
Total formula weight624.7
All*Total formula weight31049.5
*Water molecules are not included.

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PDB entries from 2026-01-28

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