8RS0
Structure of RyR1 in detergent in primed state in complex with nanobody and FKBP
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, D, H, I) | Peptidyl-prolyl cis-trans isomerase FKBP1B | polymer | 107 | 11667.3 | 4 | UniProt (Q8HYX6) Pfam (PF00254) | Oryctolagus cuniculus (rabbit) | PPIase FKBP1B,12.6 kDa FK506-binding protein,12.6 kDa FKBP,FKBP-12.6,FK506-binding protein 1B,FKBP-1B,Immunophilin FKBP12.6,Rotamase |
| 2 | E, F, G, H (B, E, G, J) | Ryanodine receptor 1 | polymer | 5027 | 564931.8 | 4 | UniProt (P11716) Pfam (PF21119) Pfam (PF01365) Pfam (PF02026) Pfam (PF08454) Pfam (PF06459) Pfam (PF00520) Pfam (PF08709) Pfam (PF02815) Pfam (PF00622) | Oryctolagus cuniculus (rabbit) | RYR-1,RyR1,Skeletal muscle calcium release channel,Skeletal muscle ryanodine receptor,Skeletal muscle-type ryanodine receptor,Type 1 ryanodine receptor |
| 3 | I, J, K, L (C, F, K, M) | Nanobody 9657 | polymer | 137 | 15125.5 | 4 | Vicugna pacos | ||
| 4 | M, Q, U, Y (B, E, G, J) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | N, R, V, Z (B, E, G, J) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 6 | AA, O, S, W (J, B, E, G) | CAFFEINE | non-polymer | 194.2 | 4 | Chemie (CFF) | |||
| 7 | BA, P, T, X (J, B, E, G) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence modifications
A, D, H, I: 1 - 107 (UniProt: Q8HYX6)
| PDB | External Database | Details |
|---|---|---|
| Asp 100 | Gly 101 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 2366898.2 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3227.4 | |
| All* | Total formula weight | 2370125.6 |
