8RRS
Structure of mouse RyR2 solubilised in detergent in open state in complex with Ca2+, ATP, caffeine and Nb9657.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, F (A, C, E, F) | Ryanodine receptor 2 | polymer | 4966 | 565536.0 | 4 | UniProt (E9Q401) Pfam (PF08709) Pfam (PF01365) Pfam (PF02026) Pfam (PF08454) Pfam (PF13499) Pfam (PF06459) Pfam (PF00520) Pfam (PF02815) Pfam (PF00622) Pfam (PF21119) | Mus musculus (house mouse) | RYR-2,RyR2,Cardiac muscle ryanodine receptor,Cardiac muscle ryanodine receptor-calcium release channel,Type 2 ryanodine receptor |
| 2 | B, D, G, H (B, D, G, I) | Nanobody 9657 | polymer | 137 | 15125.5 | 4 | Vicugna pacos | ||
| 3 | I, M, Q, U (A, C, E, F) | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 4 | Chemie (ATP) | |||
| 4 | J, N, R, V (A, C, E, F) | CAFFEINE | non-polymer | 194.2 | 4 | Chemie (CFF) | |||
| 5 | K, O, S, W (A, C, E, F) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 6 | L, P, T, X (A, C, E, F) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 2322646.0 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3227.4 | |
| All* | Total formula weight | 2325873.4 |
