8RRQ
Crystal structure of human SYK in complex with compound 24
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Tyrosine-protein kinase SYK | polymer | 282 | 32867.7 | 1 | UniProt (P43405) Pfam (PF07714) | Homo sapiens (human) | Spleen tyrosine kinase,p72-Syk |
| 2 | B (A) | N-[(1S,2R)-2-azanylcyclohexyl]-5-[2-[(3,5-dimethylphenyl)amino]pyrimidin-4-yl]-2-methyl-pyrazole-3-carboxamide | non-polymer | 419.5 | 1 | Chemie (A1H2W) | |||
| 3 | C (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 4 | D (A) | water | water | 18.0 | 178 | Chemie (HOH) |
Sequence modifications
A: 355 - 635 (UniProt: P43405)
| PDB | External Database | Details |
|---|---|---|
| Gly 354 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 32867.7 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 511.6 | |
| All* | Total formula weight | 33379.3 |
