8RRP
Insulin Icodec - A14E B16H B25H B29Ne-C20 diacid-LgGlu-2xAdo desB30 human insulin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C, E | Insulin | polymer | 21 | 2349.6 | 3 | UniProt (P01308) In PDB | Homo sapiens (human) | |
2 | B, D, F | Insulin B chain | polymer | 29 | 3298.8 | 3 | UniProt (P01308) In PDB | Homo sapiens (human) | |
3 | B, D | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
4 | water | water | 18.0 | 50 | Chemie (HOH) |
Sequence modifications
A, C, E: 1 - 21 (UniProt: P01308)
B, D, F: 1 - 29 (UniProt: P01308)
PDB | External Database | Details |
---|---|---|
Glu 14 | Tyr 103 | engineered mutation |
PDB | External Database | Details |
---|---|---|
His 16 | Tyr 40 | engineered mutation |
His 25 | Phe 49 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 16945.3 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 118.1 | |
All* | Total formula weight | 17063.4 |