8ROY
Structure of the human DDB1-DDA1-DCAF15 E3 ubiquitin ligase bound to compound furan 24
This is a non-PDB format compatible entry.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | DDB1- and CUL4-associated factor 15 | polymer | 603 | 66822.6 | 1 | UniProt (Q66K64) Pfam (PF14939) In PDB | Homo sapiens (human) | |
2 | B | DNA damage-binding protein 1 | polymer | 836 | 93347.1 | 1 | UniProt (Q16531) Pfam (PF10433) Pfam (PF03178) In PDB | Homo sapiens (human) | DDB p127 subunit,DNA damage-binding protein a,DDBa,Damage-specific DNA-binding protein 1,HBV X-associated protein 1,XAP-1,UV-damaged DNA-binding factor,UV-damaged DNA-binding protein 1,UV-DDB 1,XPE-binding factor,XPE-BF,Xeroderma pigmentosum group E-complementing protein,XPCe |
3 | D | DET1- and DDB1-associated protein 1 | polymer | 102 | 11855.3 | 1 | UniProt (Q9BW61) Pfam (PF10172) In PDB | Homo sapiens (human) | Placenta cross-immune reaction antigen 1,PCIA-1 |
4 | A | 1-[5-[[3,4-bis(chloranyl)-1~{H}-indol-7-yl]sulfamoyl]-3-methyl-furan-2-yl]carbonyl-~{N}-methyl-piperidine-4-carboxamide | non-polymer | 513.4 | 1 | Chemie (A1H18) |
Sequence modifications
A: 1 - 600 (UniProt: Q66K64)
B: 1 - 699 (UniProt: Q16531)
B: 706 - 1140 (UniProt: Q16531)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
B: 706 - 1140 (UniProt: Q16531)
PDB | External Database | Details |
---|---|---|
Gly 700 | - | linker |
Asn 701 | - | linker |
Gly 702 | - | linker |
Asn 703 | - | linker |
Ser 704 | - | linker |
Gly 705 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 3 |
Total formula weight | 172025.0 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 513.4 | |
All* | Total formula weight | 172538.4 |