8RNC
Influenza B polymerase, replication complex, an asymmetric polymerase dimer bound to human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E, F (A, X, D) | Polymerase acidic protein | polymer | 726 | 83145.0 | 3 | UniProt (Q5V8Z9) Pfam (PF00603) | Influenza B virus (B/Memphis/13/2003) | RNA-directed RNA polymerase subunit P2 |
| 2 | B, D, G (B, Y, E) | RNA-directed RNA polymerase catalytic subunit | polymer | 752 | 84433.3 | 3 | UniProt (Q5V8Y6) Pfam (PF00602) | Influenza B virus (B/Memphis/13/2003) | Polymerase basic protein 1,PB1,RNA-directed RNA polymerase subunit P1 |
| 3 | C, H (C, F) | Polymerase basic protein 2 | polymer | 799 | 90958.3 | 2 | UniProt (Q5V8X3) Pfam (PF20947) Pfam (PF20948) Pfam (PF20949) Pfam (PF20950) Pfam (PF00604) Pfam (PF20951) Pfam (PF20952) | Influenza B virus (B/Memphis/13/2003) | RNA-directed RNA polymerase subunit P3 |
| 4 | I (G) | Acidic leucine-rich nuclear phosphoprotein 32 family member A | polymer | 275 | 31747.8 | 1 | UniProt (P39687) Pfam (PF14580) | Homo sapiens (human) | Acidic nuclear phosphoprotein pp32,pp32,Leucine-rich acidic nuclear protein,LANP,Mapmodulin,Potent heat-stable protein phosphatase 2A inhibitor I1PP2A,Putative HLA-DR-associated protein I,PHAPI |
Sequence modifications
C, F: 1 - 770 (UniProt: Q5V8X3)
G: 1 - 249 (UniProt: P39687)
| PDB | External Database | Details |
|---|---|---|
| Gly 771 | - | expression tag |
| Trp 772 | - | expression tag |
| Ser 773 | - | expression tag |
| His 774 | - | expression tag |
| Pro 775 | - | expression tag |
| Gln 776 | - | expression tag |
| Phe 777 | - | expression tag |
| Glu 778 | - | expression tag |
| Lys 779 | - | expression tag |
| Gly 780 | - | expression tag |
| Gly 781 | - | expression tag |
| Gly 782 | - | expression tag |
| Ser 783 | - | expression tag |
| Gly 784 | - | expression tag |
| Gly 785 | - | expression tag |
| Gly 786 | - | expression tag |
| Ser 787 | - | expression tag |
| Gly 788 | - | expression tag |
| Gly 789 | - | expression tag |
| Ser 790 | - | expression tag |
| Ala 791 | - | expression tag |
| Trp 792 | - | expression tag |
| Ser 793 | - | expression tag |
| His 794 | - | expression tag |
| Pro 795 | - | expression tag |
| Gln 796 | - | expression tag |
| Phe 797 | - | expression tag |
| Glu 798 | - | expression tag |
| Lys 799 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Met -25 | - | initiating methionine |
| Lys -24 | - | expression tag |
| His -23 | - | expression tag |
| His -22 | - | expression tag |
| His -21 | - | expression tag |
| His -20 | - | expression tag |
| His -19 | - | expression tag |
| His -18 | - | expression tag |
| Pro -17 | - | expression tag |
| Met -16 | - | expression tag |
| Ser -15 | - | expression tag |
| Asp -14 | - | expression tag |
| Tyr -13 | - | expression tag |
| Asp -12 | - | expression tag |
| Ile -11 | - | expression tag |
| Pro -10 | - | expression tag |
| Thr -9 | - | expression tag |
| Thr -8 | - | expression tag |
| Glu -7 | - | expression tag |
| Asn -6 | - | expression tag |
| Leu -5 | - | expression tag |
| Tyr -4 | - | expression tag |
| Phe -3 | - | expression tag |
| Gln -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 716399.3 | |
| All* | Total formula weight | 716399.3 |
