8RNC

Influenza B polymerase, replication complex, an asymmetric polymerase dimer bound to human ANP32A (from "Influenza B polymerase apo-trimer" | Local refinement)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0004518	molecular_function	nuclease activity
A	0004519	molecular_function	endonuclease activity
A	0006351	biological_process	DNA-templated transcription
A	0016787	molecular_function	hydrolase activity
A	0030430	cellular_component	host cell cytoplasm
A	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
A	0039657	biological_process	symbiont-mediated suppression of host gene expression
A	0039694	biological_process	viral RNA genome replication
A	0042025	cellular_component	host cell nucleus
A	0046872	molecular_function	metal ion binding
A	0075523	biological_process	viral translational frameshifting
A	0075526	biological_process	cap snatching
B	0000166	molecular_function	nucleotide binding
B	0001172	biological_process	RNA-templated transcription
B	0003723	molecular_function	RNA binding
B	0003968	molecular_function	RNA-directed RNA polymerase activity
B	0006351	biological_process	DNA-templated transcription
B	0016740	molecular_function	transferase activity
B	0016779	molecular_function	nucleotidyltransferase activity
B	0019083	biological_process	viral transcription
B	0030430	cellular_component	host cell cytoplasm
B	0034062	molecular_function	5'-3' RNA polymerase activity
B	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
B	0039657	biological_process	symbiont-mediated suppression of host gene expression
B	0039694	biological_process	viral RNA genome replication
B	0042025	cellular_component	host cell nucleus
B	0046872	molecular_function	metal ion binding
C	0001172	biological_process	RNA-templated transcription
C	0003723	molecular_function	RNA binding
C	0003968	molecular_function	RNA-directed RNA polymerase activity
C	0006351	biological_process	DNA-templated transcription
C	0006370	biological_process	7-methylguanosine mRNA capping
C	0006397	biological_process	mRNA processing
C	0019083	biological_process	viral transcription
C	0033650	cellular_component	host cell mitochondrion
C	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
C	0039657	biological_process	symbiont-mediated suppression of host gene expression
C	0039694	biological_process	viral RNA genome replication
C	0042025	cellular_component	host cell nucleus
C	0044423	cellular_component	virion component
C	0075526	biological_process	cap snatching
D	0003723	molecular_function	RNA binding
D	0004518	molecular_function	nuclease activity
D	0004519	molecular_function	endonuclease activity
D	0006351	biological_process	DNA-templated transcription
D	0016787	molecular_function	hydrolase activity
D	0030430	cellular_component	host cell cytoplasm
D	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
D	0039657	biological_process	symbiont-mediated suppression of host gene expression
D	0039694	biological_process	viral RNA genome replication
D	0042025	cellular_component	host cell nucleus
D	0046872	molecular_function	metal ion binding
D	0075523	biological_process	viral translational frameshifting
D	0075526	biological_process	cap snatching
E	0000166	molecular_function	nucleotide binding
E	0001172	biological_process	RNA-templated transcription
E	0003723	molecular_function	RNA binding
E	0003968	molecular_function	RNA-directed RNA polymerase activity
E	0006351	biological_process	DNA-templated transcription
E	0016740	molecular_function	transferase activity
E	0016779	molecular_function	nucleotidyltransferase activity
E	0019083	biological_process	viral transcription
E	0030430	cellular_component	host cell cytoplasm
E	0034062	molecular_function	5'-3' RNA polymerase activity
E	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
E	0039657	biological_process	symbiont-mediated suppression of host gene expression
E	0039694	biological_process	viral RNA genome replication
E	0042025	cellular_component	host cell nucleus
E	0046872	molecular_function	metal ion binding
F	0001172	biological_process	RNA-templated transcription
F	0003723	molecular_function	RNA binding
F	0003968	molecular_function	RNA-directed RNA polymerase activity
F	0006351	biological_process	DNA-templated transcription
F	0006370	biological_process	7-methylguanosine mRNA capping
F	0006397	biological_process	mRNA processing
F	0019083	biological_process	viral transcription
F	0033650	cellular_component	host cell mitochondrion
F	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
F	0039657	biological_process	symbiont-mediated suppression of host gene expression
F	0039694	biological_process	viral RNA genome replication
F	0042025	cellular_component	host cell nucleus
F	0044423	cellular_component	virion component
F	0075526	biological_process	cap snatching
G	0003723	molecular_function	RNA binding
G	0005515	molecular_function	protein binding
G	0005634	cellular_component	nucleus
G	0005654	cellular_component	nucleoplasm
G	0005737	cellular_component	cytoplasm
G	0005783	cellular_component	endoplasmic reticulum
G	0006913	biological_process	nucleocytoplasmic transport
G	0035556	biological_process	intracellular signal transduction
G	0042393	molecular_function	histone binding
G	0042981	biological_process	regulation of apoptotic process
G	0048471	cellular_component	perinuclear region of cytoplasm
X	0003723	molecular_function	RNA binding
X	0004518	molecular_function	nuclease activity
X	0004519	molecular_function	endonuclease activity
X	0006351	biological_process	DNA-templated transcription
X	0016787	molecular_function	hydrolase activity
X	0030430	cellular_component	host cell cytoplasm
X	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
X	0039657	biological_process	symbiont-mediated suppression of host gene expression
X	0039694	biological_process	viral RNA genome replication
X	0042025	cellular_component	host cell nucleus
X	0046872	molecular_function	metal ion binding
X	0075523	biological_process	viral translational frameshifting
X	0075526	biological_process	cap snatching
Y	0000166	molecular_function	nucleotide binding
Y	0001172	biological_process	RNA-templated transcription
Y	0003723	molecular_function	RNA binding
Y	0003968	molecular_function	RNA-directed RNA polymerase activity
Y	0006351	biological_process	DNA-templated transcription
Y	0016740	molecular_function	transferase activity
Y	0016779	molecular_function	nucleotidyltransferase activity
Y	0019083	biological_process	viral transcription
Y	0030430	cellular_component	host cell cytoplasm
Y	0034062	molecular_function	5'-3' RNA polymerase activity
Y	0039523	biological_process	symbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
Y	0039657	biological_process	symbiont-mediated suppression of host gene expression
Y	0039694	biological_process	viral RNA genome replication
Y	0042025	cellular_component	host cell nucleus
Y	0046872	molecular_function	metal ion binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
G	THR15

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163

Chain	Residue	Details
G	SER17

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site_id	SWS_FT_FI3
Number of Residues	1
Details	MOD_RES: Phosphoserine; by CK2 => ECO:0000269|PubMed:15287743, ECO:0007744|PubMed:24275569

Chain	Residue	Details
G	SER158

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine; by CK2 => ECO:0000269|PubMed:15287743

Chain	Residue	Details
G	SER204

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