8RM9
Cryo-EM structure of human islet amyloid polypeptide (hIAPP) mutant S28P, polymorph 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (c, d, e, f, g...) | Islet amyloid polypeptide | polymer | 38 | 3917.3 | 15 | UniProt (P10997) Pfam (PF00214) | Homo sapiens | Amylin,Diabetes-associated peptide,DAP,Insulinoma amyloid peptide |
Sequence modifications
c, d, e, f, g, n, o, p, q, r, s, t, u, v, w: 1 - 37 (UniProt: P10997)
| PDB | External Database | Details |
|---|---|---|
| Pro 28 | Ser 61 | engineered mutation |
| Nh2 38 | - | amidation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 15 |
| Total formula weight | 58760.2 | |
| All* | Total formula weight | 58760.2 |
