8RM9

Cryo-EM structure of human islet amyloid polypeptide (hIAPP) mutant S28P, polymorph 2

Functional Information from GO Data

Chain	GOid	namespace	contents
c	0005179	molecular_function	hormone activity
c	0005576	cellular_component	extracellular region
d	0005179	molecular_function	hormone activity
d	0005576	cellular_component	extracellular region
e	0005179	molecular_function	hormone activity
e	0005576	cellular_component	extracellular region
f	0005179	molecular_function	hormone activity
f	0005576	cellular_component	extracellular region
g	0005179	molecular_function	hormone activity
g	0005576	cellular_component	extracellular region
n	0005179	molecular_function	hormone activity
n	0005576	cellular_component	extracellular region
o	0005179	molecular_function	hormone activity
o	0005576	cellular_component	extracellular region
p	0005179	molecular_function	hormone activity
p	0005576	cellular_component	extracellular region
q	0005179	molecular_function	hormone activity
q	0005576	cellular_component	extracellular region
r	0005179	molecular_function	hormone activity
r	0005576	cellular_component	extracellular region
s	0005179	molecular_function	hormone activity
s	0005576	cellular_component	extracellular region
t	0005179	molecular_function	hormone activity
t	0005576	cellular_component	extracellular region
u	0005179	molecular_function	hormone activity
u	0005576	cellular_component	extracellular region
v	0005179	molecular_function	hormone activity
v	0005576	cellular_component	extracellular region
w	0005179	molecular_function	hormone activity
w	0005576	cellular_component	extracellular region

Functional Information from PROSITE/UniProt

site_id	PS00258
Number of Residues	15
Details	CALCITONIN Calcitonin / CGRP / IAPP family signature. CNT.ATCAtqrLanfL

Chain	Residue	Details
c	CYS2-LEU16

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	15
Details	Modified residue: {"description":"Tyrosine amide","evidences":[{"source":"PubMed","id":"2651160","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"3053705","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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