8RHQ
Crystal structure of HLA-A*11:01 in complex with SVLNDIFSRL, an 10-mer epitope from SARS-CoV-2 Spike (S975-984)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E (A, C, E) | HLA class I histocompatibility antigen | polymer | 365 | 40985.7 | 3 | UniProt (Q5S3G3) Pfam (PF00129) Pfam (PF07654) Pfam (PF06623) | Homo sapiens (human) | HLA class I histocompatibility antigen A alpha chain,MHC class I antigen,MHC class I protein,MHC class I protein (HLA-A) |
| 2 | B, D, F (B, D, F) | Beta-2-microglobulin | polymer | 100 | 11879.4 | 3 | UniProt (P61769) Pfam (PF07654) | Homo sapiens (human) | |
| 3 | G, H, I (G, H, I) | Spike protein S2' | polymer | 10 | 1164.3 | 3 | UniProt (P0DTC2) | Severe acute respiratory syndrome coronavirus 2 | |
| 4 | BA, FA, GA, J, K... (E, F, A, B, C...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 17 | Chemie (EDO) | |||
| 5 | EA, HA, Q (E, F, B) | SODIUM ION | non-polymer | 23.0 | 3 | Chemie (NA) | |||
| 6 | V (C) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) | |||
| 7 | CA, DA, W (E, C) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 8 | AA (D) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 9 | IA, JA, KA, LA, MA... (A, B, C, D, E...) | water | water | 18.0 | 546 | Chemie (HOH) |
Sequence modifications
B, D, F: 1 - 99 (UniProt: P61769)
G, H, I: 1 - 10 (UniProt: P0DTC2)
| PDB | External Database | Details |
|---|---|---|
| Met 0 | - | initiating methionine |
| PDB | External Database | Details |
|---|---|---|
| Phe 7 | Leu 981 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 9 |
| Total formula weight | 162088.2 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 1360.9 | |
| All* | Total formula weight | 163449.2 |
