8RDZ
Crystal Structure of Human ADP-ribose Pyrophosphatase NUDT5 In complex with Ibrutinib
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | ADP-sugar pyrophosphatase | polymer | 219 | 24355.6 | 4 | UniProt (Q9UKK9) Pfam (PF00293) In PDB | Homo sapiens (human) | 8-oxo-dGDP phosphatase,Nuclear ATP-synthesis protein NUDIX5,Nucleoside diphosphate-linked moiety X motif 5,Nudix motif 5,hNUDT5,YSA1H |
| 2 | A, B, C, D | MAGNESIUM ION | non-polymer | 24.3 | 8 | Chemie (MG) | |||
| 3 | A, B, C, D | Ibrutinib (unbound form) | non-polymer | 440.5 | 4 | Chemie (A1H14) | |||
| 4 | B, C, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 5 | water | water | 18.0 | 119 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 97422.4 | |
| Non-Polymers* | Number of molecules | 19 |
| Total formula weight | 2390.9 | |
| All* | Total formula weight | 99813.3 |
