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8RDT

Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with spiro-isoxazol based compound 8j

This is a non-PDB format compatible entry.
Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, CCereblon isoform 4polymer12513703.63UniProt (A4TVL0)
In PDB
Magnetospirillum gryphiswaldense
2A, B, CZINC IONnon-polymer65.43Chemie (ZN)
3A, B(5~{S})-3-(2,3,4-trimethoxyphenyl)-1-oxa-2,9-diazaspiro[4.5]dec-2-ene-8,10-dionenon-polymer334.32Chemie (A1HZ2)
4APHOSPHATE IONnon-polymer95.01Chemie (PO4)
5waterwater18.056Chemie (HOH)
Sequence modifications
A, B, C: 1 - 124 (UniProt: A4TVL0)
PDBExternal DatabaseDetails
Ala 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight41110.7
Non-Polymers*Number of molecules6
Total formula weight959.8
All*Total formula weight42070.6
*Water molecules are not included.

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PDB entries from 2024-07-17

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