8RDH

Crystal structure of UDP-galactose 4-epimerase from Pyrococcus horikoshii with bound NAD and GDP-L-fucose

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	SDR family NAD(P)-dependent oxidoreductase	polymer	326	36711.8	2	UniProt (A0A832T930) UniProt (by SIFTS) (O73960)	Pyrococcus horikoshii
2	C, E (A, B)	NICOTINAMIDE-ADENINE-DINUCLEOTIDE	non-polymer		663.4	2	Chemie (NAD)
3	D, F (A, B)	GUANOSINE-5'-DIPHOSPHATE-BETA-L-FUCOPYRANOSE	non-polymer		589.3	2	Chemie (GFB) PubChem (135412609) PubChem (135432122) PubChem (135618130) PubChem (135820750) PubChem (135857542) PubChem (136771500) PubChem (137034801) PubChem (137286751) PubChem (154728870) PubChem (162951224) PubChem (171699380) PubChem (135398578) PubChem (135398655) PubChem (135398688) PubChem (135398715) PubChem (135402013) PubChem (135410864) PubChem (135442158) PubChem (135665286) PubChem (135815440) PubChem (135815442) PubChem (135829314) PubChem (136044550) PubChem (136153884) PubChem (136254584) PubChem (136597497) PubChem (136597502) PubChem (136649460) PubChem (136663939) PubChem (137105976) PubChem (137105977) PubChem (137105978) PubChem (137270783) PubChem (138454237) PubChem (169441079) PubChem (171439195)
4	G, H (A, B)	water	water		18.0	68	Chemie (HOH)

Sequence modifications

A, B: 1 - 318 (UniProt: A0A832T930)

PDB	External Database	Details
Leu 319	-	expression tag
Glu 320	-	expression tag
His 321	-	expression tag
His 322	-	expression tag
His 323	-	expression tag
His 324	-	expression tag
His 325	-	expression tag
His 326	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	73423.6
Non-Polymers*	Number of molecules	4
	Total formula weight	2505.5
All*	Total formula weight	75929.1

*Water molecules are not included.