8RD4

Telomeric RAP1:DNA-PK complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	DNA-dependent protein kinase catalytic subunit	polymer	4128	469673.2	1	UniProt (P78527) Pfam (PF20502) Pfam (PF08163) Pfam (PF19704) Pfam (PF02259) Pfam (PF00454) Pfam (PF02260)	Homo sapiens (human)	DNA-PK catalytic subunit,DNA-PKcs,DNPK1,p460
2	B (D)	Telomeric repeat-binding factor 2-interacting protein 1	polymer	399	44314.9	1	UniProt (Q9NYB0) Pfam (PF16589) Pfam (PF08914) Pfam (PF11626)	Homo sapiens (human)
3	C (E)	X-ray repair cross-complementing protein 6	polymer	609	69945.0	1	UniProt (P12956) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF02037)	Homo sapiens (human)	5'-deoxyribose-5-phosphate lyase Ku70,5'-dRP lyase Ku70,70 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 1,ATP-dependent DNA helicase II 70 kDa subunit,CTC box-binding factor 75 kDa subunit,CTCBF,DNA repair protein XRCC6,Lupus Ku autoantigen protein p70,Ku70,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 6
4	D (F)	X-ray repair cross-complementing protein 5	polymer	732	82812.4	1	UniProt (P13010) Pfam (PF03731) Pfam (PF02735) Pfam (PF03730) Pfam (PF08785)	Homo sapiens (human)	86 kDa subunit of Ku antigen,ATP-dependent DNA helicase 2 subunit 2,ATP-dependent DNA helicase II 80 kDa subunit,CTC box-binding factor 85 kDa subunit,CTCBF,DNA repair protein XRCC5,Ku80,Ku86,Lupus Ku autoantigen protein p86,Nuclear factor IV,Thyroid-lupus autoantigen,TLAA,X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
5	E (X)	DNA (41-MER)	polymer	100	31103.8	1		synthetic construct
6	F (Y)	DNA (41-MER)	polymer	100	30589.7	1		synthetic construct

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	728439.1
All*	Total formula weight	728439.1

*Water molecules are not included.