8R8P

Solution structure of SMN-CX bound to the RNA helix formed upon SMN2 exon7 5'-splice site recognition

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	RNA (5'-R(*AP*UP*AP*CP*(PSU)P*(PSU)P*AP*CP*CP*UP*G)-3')	polymer	11	3428.1	1		Homo sapiens
2	B	RNA (5'-R(P*GP*GP*AP*GP*UP*AP*AP*GP*UP*CP*U)-3')	polymer	11	3547.2	1		Homo sapiens
3	B	2-(8-fluoranyl-2-methyl-imidazo[1,2-a]pyridin-6-yl)-6-(4-methylpiperazin-1-yl)quinazoline	non-polymer		376.4	1	Chemie (YB3)

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	6975.2
Non-Polymers*	Number of molecules	1
	Total formula weight	376.4
All*	Total formula weight	7351.7

*Water molecules are not included.