8R7L
Cryo-EM structure of the human TREX complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (H) | Spliceosome RNA helicase DDX39B | polymer | 428 | 49056.3 | 1 | UniProt (Q13838) Pfam (PF00271) Pfam (PF00270) | Homo sapiens (human) | 56 kDa U2AF65-associated protein,ATP-dependent RNA helicase p47,DEAD box protein UAP56,HLA-B-associated transcript 1 protein |
| 2 | B (A) | THO complex subunit 1 | polymer | 657 | 75752.2 | 1 | UniProt (Q96FV9) Pfam (PF11957) Pfam (PF00531) | Homo sapiens (human) | Tho1,Nuclear matrix protein p84,p84N5,hTREX84 |
| 3 | C (B) | THO complex subunit 2 | polymer | 1593 | 183087.7 | 1 | UniProt (Q8NI27) Pfam (PF16134) Pfam (PF11732) Pfam (PF11262) | Homo sapiens (human) | Tho2,hTREX120 |
| 4 | D (C) | THO complex subunit 3 | polymer | 351 | 38817.6 | 1 | UniProt (Q96J01) Pfam (PF25174) | Homo sapiens (human) | Tho3,TEX1 homolog,hTREX45 |
| 5 | E (D) | THO complex subunit 4 | polymer | 183 | 19233.6 | 1 | UniProt (Q86V81) Pfam (PF00076) | Homo sapiens (human) | Tho4,Ally of AML-1 and LEF-1,Aly/REF export factor,Transcriptional coactivator Aly/REF,bZIP-enhancing factor BEF |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 5 |
| Total formula weight | 365947.4 | |
| All* | Total formula weight | 365947.4 |
