8R64
Cryo-EM structure of the FIGNL1 AAA hexamer bound to RAD51
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | B, C, D, E, F... | Fidgetin-like protein 1 | polymer | 417 | 46154.5 | 6 | UniProt (Q6PIW4) Pfam (PF00004) Pfam (PF17862) Pfam (PF09336) In PDB | Homo sapiens (human) | |
2 | G | DNA repair protein RAD51 homolog 1 | polymer | 339 | 37009.1 | 1 | UniProt (Q06609) Pfam (PF14520) Pfam (PF08423) In PDB | Homo sapiens (human) | HsRAD51,hRAD51,RAD51 homolog A |
3 | B, C, D, E, F... | MAGNESIUM ION | non-polymer | 24.3 | 6 | Chemie (MG) | |||
4 | B, C, D, E, A | ADENOSINE-5'-TRIPHOSPHATE | non-polymer | 507.2 | 5 | Chemie (ATP) | |||
5 | F | ADENOSINE-5'-DIPHOSPHATE | non-polymer | 427.2 | 1 | Chemie (ADP) |
Sequence modifications
B, C, D, E, F, A: 284 - 674 (UniProt: Q6PIW4)
PDB | External Database | Details |
---|---|---|
Met 268 | - | initiating methionine |
Ala 269 | - | expression tag |
His 270 | - | expression tag |
His 271 | - | expression tag |
His 272 | - | expression tag |
His 273 | - | expression tag |
His 274 | - | expression tag |
His 275 | - | expression tag |
Ser 276 | - | expression tag |
Ser 277 | - | expression tag |
Gly 278 | - | expression tag |
Leu 279 | - | expression tag |
Glu 280 | - | expression tag |
Val 281 | - | expression tag |
Leu 282 | - | expression tag |
Phe 283 | - | expression tag |
Gln 284 | Asn 284 | conflict |
Gln 501 | Glu 501 | engineered mutation |
Ser 675 | - | expression tag |
Ala 676 | - | expression tag |
Trp 677 | - | expression tag |
Ser 678 | - | expression tag |
His 679 | - | expression tag |
Pro 680 | - | expression tag |
Gln 681 | - | expression tag |
Phe 682 | - | expression tag |
Glu 683 | - | expression tag |
Lys 684 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 7 |
Total formula weight | 313936.1 | |
Non-Polymers* | Number of molecules | 12 |
Total formula weight | 3108.9 | |
All* | Total formula weight | 317045.1 |