8R64
Cryo-EM structure of the FIGNL1 AAA hexamer bound to RAD51
Functional Information from PROSITE/UniProt
| site_id | PS00674 |
| Number of Residues | 20 |
| Details | AAA AAA-protein family signature. IlVVgATNrpqeIDeAArrR |
| Chain | Residue | Details |
| B | ILE539-ARG558 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255 |
| Chain | Residue | Details |
| G | GLY127 | |
| F | GLY444 | |
| A | ALA404 | |
| A | GLY444 | |
| B | GLY444 | |
| C | ALA404 | |
| C | GLY444 | |
| D | ALA404 | |
| D | GLY444 | |
| E | ALA404 | |
| E | GLY444 | |
| F | ALA404 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: N-acetylalanine => ECO:0007744|PubMed:22814378 |
| Chain | Residue | Details |
| G | ALA2 | |
| C | LYS339 | |
| D | LYS339 | |
| E | LYS339 | |
| F | LYS339 | |
| A | LYS339 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by CK2 => ECO:0000269|PubMed:22325354, ECO:0000269|PubMed:26811421 |
| Chain | Residue | Details |
| G | THR13 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by PLK1 => ECO:0000269|PubMed:22325354, ECO:0000269|PubMed:26811421 |
| Chain | Residue | Details |
| G | SER14 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphotyrosine; by ABL1 => ECO:0000269|PubMed:9461559 |
| Chain | Residue | Details |
| G | TYR54 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by CHEK1 => ECO:0000269|PubMed:15665856 |
| Chain | Residue | Details |
| G | THR309 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 3 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:23393192 |
| Chain | Residue | Details |
| G | LYS58 | |
| G | LYS64 |
