8R5C
Crystal structure of human TRIM7 PRYSPRY domain bound to (2-(1-oxoisoindolin-2-yl)-3-phenylpropanoyl)-L-glutamine
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A (A) | E3 ubiquitin-protein ligase TRIM7 | polymer | 175 | 19746.3 | 1 | UniProt (Q9C029) Pfam (PF13765) Pfam (PF00622) | Homo sapiens (human) | |
2 | B (A) | (2~{S})-5-azanyl-5-oxidanylidene-2-[[(2~{S})-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)-3-phenyl-propanoyl]amino]pentanoic acid | non-polymer | 409.4 | 1 | Chemie (Y3C) | |||
3 | C, D, E (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
4 | F, G (A) | S,R MESO-TARTARIC ACID | non-polymer | 150.1 | 2 | Chemie (SRT) | |||
5 | H (A) | water | water | 18.0 | 153 | Chemie (HOH) |
Sequence modifications
A: 338 - 511 (UniProt: Q9C029)
PDB | External Database | Details |
---|---|---|
Gly 337 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 19746.3 | |
Non-Polymers* | Number of molecules | 6 |
Total formula weight | 895.8 | |
All* | Total formula weight | 20642.2 |