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8R5C

Crystal structure of human TRIM7 PRYSPRY domain bound to (2-(1-oxoisoindolin-2-yl)-3-phenylpropanoyl)-L-glutamine

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
E3 ubiquitin-protein ligase TRIM7polymer17519746.31UniProt (Q9C029)
Pfam (PF13765)
Pfam (PF00622)
Homo sapiens (human)
2B
(A)
(2~{S})-5-azanyl-5-oxidanylidene-2-[[(2~{S})-2-(3-oxidanylidene-1~{H}-isoindol-2-yl)-3-phenyl-propanoyl]amino]pentanoic acidnon-polymer409.41Chemie (Y3C)
3C, D, E
(A)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
4F, G
(A)
S,R MESO-TARTARIC ACIDnon-polymer150.12Chemie (SRT)
5H
(A)
waterwater18.0153Chemie (HOH)
Sequence modifications
A: 338 - 511 (UniProt: Q9C029)
PDBExternal DatabaseDetails
Gly 337-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight19746.3
Non-Polymers*Number of molecules6
Total formula weight895.8
All*Total formula weight20642.2
*Water molecules are not included.

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PDB entries from 2025-07-16

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