8R3R

Transketolase from Streptococcus pneumoniae in complex with thiamin pyrophosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Probable transketolase	polymer	673	73092.5	4	UniProt (P22976) Pfam (PF00456) Pfam (PF02779) Pfam (PF02780)	Streptococcus pneumoniae	TK
2	E, I, K, M (A, B, C, D)	THIAMINE DIPHOSPHATE	non-polymer		425.3	4	Chemie (TPP)
3	F, H (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	2	Chemie (EDO)
4	G, J, L, N (A, B, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
5	O, P, Q, R (A, B, C, D)	water	water		18.0	2364	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 658 (UniProt: P22976)

PDB	External Database	Details
Glu 659	-	expression tag
Asn 660	-	expression tag
Leu 661	-	expression tag
Tyr 662	-	expression tag
Phe 663	-	expression tag
Gln 664	-	expression tag
Gly 665	-	expression tag
Leu 666	-	expression tag
Glu 667	-	expression tag
His 668	-	expression tag
His 669	-	expression tag
His 670	-	expression tag
His 671	-	expression tag
His 672	-	expression tag
His 673	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	292369.9
Non-Polymers*	Number of molecules	10
	Total formula weight	1922.6
All*	Total formula weight	294292.5

*Water molecules are not included.