8R3R

Transketolase from Streptococcus pneumoniae in complex with thiamin pyrophosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004802	molecular_function	transketolase activity
A	0005829	cellular_component	cytosol
A	0006098	biological_process	pentose-phosphate shunt
A	0016744	molecular_function	transketolase or transaldolase activity
B	0004802	molecular_function	transketolase activity
B	0005829	cellular_component	cytosol
B	0006098	biological_process	pentose-phosphate shunt
B	0016744	molecular_function	transketolase or transaldolase activity
C	0004802	molecular_function	transketolase activity
C	0005829	cellular_component	cytosol
C	0006098	biological_process	pentose-phosphate shunt
C	0016744	molecular_function	transketolase or transaldolase activity
D	0004802	molecular_function	transketolase activity
D	0005829	cellular_component	cytosol
D	0006098	biological_process	pentose-phosphate shunt
D	0016744	molecular_function	transketolase or transaldolase activity

Functional Information from PROSITE/UniProt

site_id	PS00801
Number of Residues	21
Details	TRANSKETOLASE_1 Transketolase signature 1. RflgIDainkanSGHPGvvMG

Chain	Residue	Details
A	ARG10-GLY30

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site_id	PS00802
Number of Residues	17
Details	TRANSKETOLASE_2 Transketolase signature 2. GEDGPTHePVEhlAglR

Chain	Residue	Details
A	GLY464-ARG480

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"38767928","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	32
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"P27302","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"PubMed","id":"38767928","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"8R3R","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	8
Details	Site: {"description":"Important for catalytic activity","evidences":[{"source":"PubMed","id":"38767928","evidenceCode":"ECO:0000305"}]}

Chain

Residue

Details

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