8R3Q

Transketolase from Plasmodium falciparum in complex with thiamin pyrophosphate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (B, A, C, D)	transketolase	polymer	687	77833.1	4	UniProt (C6KSV3) Pfam (PF00456) Pfam (PF02779) Pfam (PF22613)	Plasmodium falciparum (malaria parasite P. falciparum)
2	E, J, N, R (B, A, C, D)	THIAMINE DIPHOSPHATE	non-polymer		425.3	4	Chemie (TPP)
3	F, K, O, S (B, A, C, D)	CITRIC ACID	non-polymer		192.1	4	Chemie (CIT)
4	G, I, L, P, T (B, A, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
5	H, M, Q, U (B, A, C, D)	MAGNESIUM ION	non-polymer		24.3	4	Chemie (MG)
6	V, W, X, Y (B, A, C, D)	water	water		18.0	2929	Chemie (HOH)

Sequence modifications

B, A, C, D: 1 - 672 (UniProt: C6KSV3)

PDB	External Database	Details
Glu 673	-	expression tag
Asn 674	-	expression tag
Leu 675	-	expression tag
Tyr 676	-	expression tag
Phe 677	-	expression tag
Gln 678	-	expression tag
Gly 679	-	expression tag
Leu 680	-	expression tag
Glu 681	-	expression tag
His 682	-	expression tag
His 683	-	expression tag
His 684	-	expression tag
His 685	-	expression tag
His 686	-	expression tag
His 687	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	311332.2
Non-Polymers*	Number of molecules	17
	Total formula weight	2877.3
All*	Total formula weight	314209.6

*Water molecules are not included.