8R1J
Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, D) | Polymerase acidic protein | polymer | 716 | 82600.3 | 2 | UniProt (A5Z236) | Influenza A virus | |
| 2 | B, E (B, E) | RNA-directed RNA polymerase catalytic subunit | polymer | 757 | 86616.3 | 2 | UniProt (A5Z231) | Influenza A virus | |
| 3 | C, F (C, F) | Polymerase basic protein 2 | polymer | 898 | 101380.0 | 2 | UniProt (by SIFTS) (A5Z230) | Influenza A virus | |
| 4 | G (G) | Acidic leucine-rich nuclear phosphoprotein 32 family member B | polymer | 251 | 28816.7 | 1 | UniProt (Q92688) Pfam (PF12799) | Homo sapiens (human) |
Sequence modifications
A, D: 4 - 716 (UniProt: A5Z236)
B, E: 4 - 757 (UniProt: A5Z231)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | variant |
| Glu 2 | - | variant |
| Asp 3 | - | variant |
| Arg 556 | Gln 553 | engineered mutation |
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | variant |
| Asp 2 | - | variant |
| Val 3 | - | variant |
| Glu 577 | Lys 574 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 570009.9 | |
| All* | Total formula weight | 570009.9 |
