8R1J
Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B.
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Polymerase acidic protein | polymer | 716 | 82600.3 | 2 | UniProt (A5Z236) Pfam (PF00603) In PDB | Influenza A virus | |
2 | B, E | RNA-directed RNA polymerase catalytic subunit | polymer | 757 | 86616.3 | 2 | UniProt (A5Z231) Pfam (PF00602) In PDB | Influenza A virus | |
3 | C, F | Polymerase basic protein 2 | polymer | 898 | 101380.0 | 2 | Pfam (PF20947) Pfam (PF20948) Pfam (PF20949) Pfam (PF20950) Pfam (PF00604) Pfam (PF20951) Pfam (PF20952) UniProt (by SIFTS) (A5Z230) In PDB | Influenza A virus | |
4 | G | Acidic leucine-rich nuclear phosphoprotein 32 family member B | polymer | 251 | 28816.7 | 1 | UniProt (Q92688) Pfam (PF12799) In PDB | Homo sapiens (human) |
Sequence modifications
A, D: 4 - 716 (UniProt: A5Z236)
B, E: 4 - 757 (UniProt: A5Z231)
PDB | External Database | Details |
---|---|---|
Met 1 | - | variant |
Glu 2 | - | variant |
Asp 3 | - | variant |
Arg 556 | Gln 553 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Met 1 | - | variant |
Asp 2 | - | variant |
Val 3 | - | variant |
Glu 577 | Lys 574 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 7 |
Total formula weight | 570009.9 | |
All* | Total formula weight | 570009.9 |