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8R1J

Structure of avian H5N1 influenza A polymerase dimer in complex with human ANP32B.

Functional Information from GO Data
ChainGOidnamespacecontents
A0004519molecular_functionendonuclease activity
A0030430cellular_componenthost cell cytoplasm
A0039523biological_processsymbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
A0042025cellular_componenthost cell nucleus
A0046872molecular_functionmetal ion binding
A0075523biological_processviral translational frameshifting
A0075526biological_processcap snatching
B0000166molecular_functionnucleotide binding
B0001172biological_processRNA-templated transcription
B0003968molecular_functionRNA-dependent RNA polymerase activity
B0005737cellular_componentcytoplasm
B0019083biological_processviral transcription
B0030430cellular_componenthost cell cytoplasm
B0034062molecular_function5'-3' RNA polymerase activity
B0039523biological_processsymbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
B0042025cellular_componenthost cell nucleus
D0004519molecular_functionendonuclease activity
D0030430cellular_componenthost cell cytoplasm
D0039523biological_processsymbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
D0042025cellular_componenthost cell nucleus
D0046872molecular_functionmetal ion binding
D0075523biological_processviral translational frameshifting
D0075526biological_processcap snatching
E0000166molecular_functionnucleotide binding
E0001172biological_processRNA-templated transcription
E0003968molecular_functionRNA-dependent RNA polymerase activity
E0005737cellular_componentcytoplasm
E0019083biological_processviral transcription
E0030430cellular_componenthost cell cytoplasm
E0034062molecular_function5'-3' RNA polymerase activity
E0039523biological_processsymbiont-mediated suppression of host mRNA transcription via inhibition of RNA polymerase II activity
E0042025cellular_componenthost cell nucleus
G0001944biological_processvasculature development
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005654cellular_componentnucleoplasm
G0005730cellular_componentnucleolus
G0005737cellular_componentcytoplasm
G0006334biological_processnucleosome assembly
G0006919biological_processactivation of cysteine-type endopeptidase activity involved in apoptotic process
G0021591biological_processventricular system development
G0042393molecular_functionhistone binding
G0042981biological_processregulation of apoptotic process
G0045596biological_processnegative regulation of cell differentiation
G0046827biological_processpositive regulation of protein export from nucleus
G0048839biological_processinner ear development
G0060021biological_processroof of mouth development
G0070062cellular_componentextracellular exosome
G0070063molecular_functionRNA polymerase binding
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
GLYS86

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:Q9EST6
ChainResidueDetails
GSER158

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0000269|PubMed:17178712, ECO:0007744|PubMed:17081983, ECO:0007744|PubMed:18318008, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163, ECO:0007744|PubMed:24275569
ChainResidueDetails
GTHR244

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PDB entries from 2024-07-24

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