8R0Q
Pim1 in complex with 6-bromo-1H-benzo[d]imidazol-2-amine and Pimtide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Serine/threonine-protein kinase pim-1 | polymer | 313 | 35670.5 | 1 | UniProt (P11309) Pfam (PF00069) | Homo sapiens (human) | |
| 2 | B (B) | Pimtide | polymer | 14 | 1592.8 | 1 | Homo sapiens | ||
| 3 | C (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 4 | D (A) | 6-bromo-1H-benzo[d]imidazol-2-amine | non-polymer | 212.0 | 1 | Chemie (XGB) | |||
| 5 | E (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | F, G (A, B) | water | water | 18.0 | 190 | Chemie (HOH) |
Sequence modifications
A: 1 - 312 (UniProt: P11309)
| PDB | External Database | Details |
|---|---|---|
| Ser 0 | - | expression tag |
| Gly 250 | Arg 250 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 37263.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 309.6 | |
| All* | Total formula weight | 37572.9 |
