8QZD

Soluble epoxide hydrolase in complex with Epoxykinin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	Bifunctional epoxide hydrolase 2	polymer	367	41951.1	1	UniProt (P34913) Pfam (PF00561) In PDB	Homo sapiens (human)
2	A	1,2-ETHANEDIOL	non-polymer		62.1	12	Chemie (EDO)
3	A	2-[5-bromanyl-3-[2,2,2-tris(fluoranyl)ethanoyl]indol-1-yl]-N-cycloheptyl-ethanamide	non-polymer		445.3	1	Chemie (XDZ)
4	A	BROMIDE ION	non-polymer		79.9	1	Chemie (BR)
5		water	water		18.0	258	Chemie (HOH)

Sequence modifications

A: 222 - 555 (UniProt: P34913)

PDB	External Database	Details
Met 198	-	initiating methionine
Gly 199	-	expression tag
Ser 200	-	expression tag
Ser 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag
His 204	-	expression tag
His 205	-	expression tag
His 206	-	expression tag
His 207	-	expression tag
Ser 208	-	expression tag
Ser 209	-	expression tag
Gly 210	-	expression tag
Leu 211	-	expression tag
Val 212	-	expression tag
Pro 213	-	expression tag
Arg 214	-	expression tag
Gly 215	-	expression tag
Ser 216	-	expression tag
His 217	-	expression tag
Met 218	-	expression tag
Ala 219	-	expression tag
Ser 220	-	expression tag
Met 221	-	expression tag
Leu 556	-	expression tag
Leu 557	-	expression tag
Glu 558	-	expression tag
His 559	-	expression tag
His 560	-	expression tag
His 561	-	expression tag
His 562	-	expression tag
His 563	-	expression tag
His 564	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	41951.1
Non-Polymers*	Number of molecules	14
	Total formula weight	1270.0
All*	Total formula weight	43221.1

*Water molecules are not included.