8QZ1
Crystal structure of human two pore domain potassium ion channel TREK-2 (K2P10.1) in complex with a nanobody (Nb58)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Isoform B of Potassium channel subfamily K member 10 | polymer | 282 | 31060.1 | 2 | UniProt (P57789) Pfam (PF00520) Pfam (PF07885) In PDB | Homo sapiens (human) | |
| 2 | C, D | Nanobody 58 | polymer | 136 | 14783.2 | 2 | Lama glama | ||
| 3 | A, B | POTASSIUM ION | non-polymer | 39.1 | 3 | Chemie (K) |
Sequence modifications
A, B: 67 - 340 (UniProt: P57789)
| PDB | External Database | Details |
|---|---|---|
| Met 66 | - | initiating methionine |
| Ala 341 | - | expression tag |
| Glu 342 | - | expression tag |
| Asn 343 | - | expression tag |
| Leu 344 | - | expression tag |
| Tyr 345 | - | expression tag |
| Phe 346 | - | expression tag |
| Gln 347 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 91686.6 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 117.3 | |
| All* | Total formula weight | 91803.9 |
