8QYA
J22.9-FNY, fully humanized, CDR optimized Fab Fragment based on chimeric J22.9-xi IgG against BCMA; with VH CDR2 glycosylation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (L) | J22.9-FNY Fab antibody light chain | polymer | 214 | 23321.8 | 1 | Mus musculus | ||
| 2 | B (H) | J22.9-FNY Fab antibody heavy chain | polymer | 216 | 23141.8 | 1 | Mus musculus | ||
| 3 | C (A) | Tumor necrosis factor receptor superfamily member 17 | polymer | 36 | 4083.6 | 1 | UniProt (Q02223) Pfam (PF09257) | Homo sapiens (human) | B-cell maturation protein |
| 4 | D (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 5 | E (H) | COPPER (II) ION | non-polymer | 63.5 | 1 | Chemie (CU) | |||
| 6 | F, G, H (L, H, A) | water | water | 18.0 | 74 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 50547.3 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 63.5 | |
| All* | Total formula weight | 51035.3 |
