8QY6
Structure of interleukin 6 (gp130 P496L mutant).
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, F (A, D) | Interleukin-6 receptor subunit beta | polymer | 917 | 102568.9 | 2 | UniProt (Q00560) Pfam (PF06328) Pfam (PF25552) Pfam (PF00041) | Mus musculus (house mouse) | |
| 2 | B, D (B, E) | Interleukin-6 | polymer | 212 | 23743.2 | 2 | UniProt (P05231) Pfam (PF00489) | Homo sapiens (human) | |
| 3 | C, E (C, F) | Interleukin-6 receptor subunit alpha | polymer | 468 | 51605.3 | 2 | UniProt (P08887) Pfam (PF00047) Pfam (PF09240) | Homo sapiens (human) | |
| 4 | G, H, I, J, K... (G, H, I, J, K...) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 10 | In PDB GlyTouCan (G42666HT) | |||
| 5 | Q, R (A, D) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, D: 1 - 917 (UniProt: Q00560)
| PDB | External Database | Details |
|---|---|---|
| Leu 496 | Pro 496 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 355834.9 | |
| Branched | Number of molecules | 10 |
| Total formula weight | 4244.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 442.4 | |
| All* | Total formula weight | 360521.3 |
