8QY6
Structure of interleukin 6 (gp130 P496L mutant).
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, D | Interleukin-6 receptor subunit beta | polymer | 917 | 102568.9 | 2 | UniProt (Q00560) Pfam (PF06328) Pfam (PF09240) Pfam (PF00041) In PDB | Mus musculus (house mouse) | |
2 | B, E | Interleukin-6 | polymer | 212 | 23743.2 | 2 | UniProt (P05231) Pfam (PF00489) In PDB | Homo sapiens (human) | |
3 | C, F | Interleukin-6 receptor subunit alpha | polymer | 468 | 51605.3 | 2 | UniProt (P08887) Pfam (PF00047) Pfam (PF09240) In PDB | Homo sapiens (human) | |
4 | G, H, I, J, K... | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 10 | In PDB GlyTouCan (G42666HT) | |||
5 | A, D | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) |
Sequence modifications
A, D: 1 - 917 (UniProt: Q00560)
PDB | External Database | Details |
---|---|---|
Leu 496 | Pro 496 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 6 |
Total formula weight | 355834.9 | |
Branched | Number of molecules | 10 |
Total formula weight | 4244.0 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 442.4 | |
All* | Total formula weight | 360521.3 |