Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004896 | molecular_function | cytokine receptor activity |
| A | 0016020 | cellular_component | membrane |
| B | 0005125 | molecular_function | cytokine activity |
| B | 0005138 | molecular_function | interleukin-6 receptor binding |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005615 | cellular_component | extracellular space |
| B | 0006955 | biological_process | immune response |
| B | 0030154 | biological_process | cell differentiation |
| C | 0004896 | molecular_function | cytokine receptor activity |
| C | 0016020 | cellular_component | membrane |
| D | 0004896 | molecular_function | cytokine receptor activity |
| D | 0016020 | cellular_component | membrane |
| E | 0005125 | molecular_function | cytokine activity |
| E | 0005138 | molecular_function | interleukin-6 receptor binding |
| E | 0005576 | cellular_component | extracellular region |
| E | 0005615 | cellular_component | extracellular space |
| E | 0006955 | biological_process | immune response |
| E | 0030154 | biological_process | cell differentiation |
| F | 0004896 | molecular_function | cytokine receptor activity |
| F | 0016020 | cellular_component | membrane |
Functional Information from PROSITE/UniProt
| site_id | PS00254 |
| Number of Residues | 26 |
| Details | INTERLEUKIN_6 Interleukin-6 / G-CSF / MGF signature. CfqsgfneetClvkiitGLleFevyL |
| Chain | Residue | Details |
| B | CYS73-LEU98 | |
| site_id | PS01353 |
| Number of Residues | 54 |
| Details | HEMATOPO_REC_L_F2 Long hematopoietin receptor, gp130 family signature. NkvgkSaaavltipsphvtaaysvvnlkafpkdnllw....VeWtppPkpvsk....Yi.LeW |
| Chain | Residue | Details |
| A | ASN402-TRP455 | |
| site_id | PS01354 |
| Number of Residues | 42 |
| Details | HEMATOPO_REC_L_F3 Long hematopoietin receptor, soluble alpha chains family signature. LqPDPPanItvtavarnprwLsvtWqdPhSWnssf..YrLrFeL |
| Chain | Residue | Details |
| C | LEU195-LEU236 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 690 |
| Details | TOPO_DOM: Extracellular => ECO:0000255 |
| Chain | Residue | Details |
| C | LEU1-PRO346 | |
| F | LEU1-PRO346 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| C | THR347-LEU367 | |
| F | THR347-LEU367 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 162 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000255 |
| Chain | Residue | Details |
| C | ARG368-ARG449 | |
| F | ARG368-ARG449 | |
| Chain | Residue | Details |
| C | ASN226 | |
| D | SER837 | |
| F | ASN226 | |
| A | SER780 | |
| A | SER827 | |
| A | SER837 | |
| D | SER659 | |
| D | SER665 | |
| D | SER780 | |
| D | SER827 | |
| Chain | Residue | Details |
| C | PRO336 | |
| F | PRO336 | |
| Chain | Residue | Details |
| C | ASN36 | |
| D | ASN61 | |
| D | ASN83 | |
| D | ASN131 | |
| D | ASN157 | |
| D | ASN388 | |
| D | ASN476 | |
| D | ASN551 | |
| C | ASN74 | |
| C | ASN202 | |
| F | ASN36 | |
| F | ASN74 | |
| F | ASN202 | |
| A | ASN476 | |
| A | ASN551 | |
| D | ASN43 | |
| Chain | Residue | Details |
| C | ASN226 | |
| C | ASN331 | |
| F | ASN226 | |
| F | ASN331 | |
| Chain | Residue | Details |
| C | THR333 | |
| F | THR333 | |
