8QXK
Cryo-EM structure of tetrameric human SAMHD1 State I - Tense
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, C, B, D) | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | polymer | 626 | 72305.4 | 4 | UniProt (Q9Y3Z3) Pfam (PF07647) Pfam (PF01966) | Homo sapiens (human) | |
| 2 | AA, E, L, T (D, A, C, B) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 4 | Chemie (GTP) | |||
| 3 | BA, F, M, U (D, A, C, B) | FE (III) ION | non-polymer | 55.8 | 4 | Chemie (FE) | |||
| 4 | CA, DA, EA, G, H... (D, A, C, B) | MAGNESIUM ION | non-polymer | 24.3 | 12 | Chemie (MG) | |||
| 5 | FA, J, Q, Y (D, A, C, B) | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE | non-polymer | 467.2 | 4 | Chemie (DCP) | |||
| 6 | K, R, S, Z (A, C, B, D) | 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE | non-polymer | 491.2 | 4 | Chemie (DTP) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 289221.7 | |
| Non-Polymers* | Number of molecules | 28 |
| Total formula weight | 6441.1 | |
| All* | Total formula weight | 295662.8 |
