8QWO
Structure of p53 cancer mutant Y234C
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Cellular tumor antigen p53 | polymer | 219 | 24530.8 | 2 | UniProt (P04637) Pfam (PF00870) | Homo sapiens (human) | |
| 2 | C, E (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, F (A, B) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | G, H (A, B) | water | water | 18.0 | 551 | Chemie (HOH) |
Sequence modifications
A, B: 94 - 312 (UniProt: P04637)
| PDB | External Database | Details |
|---|---|---|
| Leu 133 | Met 133 | conflict |
| Ala 203 | Val 203 | conflict |
| Cys 234 | Tyr 234 | engineered mutation |
| Tyr 239 | Asn 239 | conflict |
| Asp 268 | Asn 268 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49061.6 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 315.0 | |
| All* | Total formula weight | 49376.6 |
