8QSL
Cryo-EM structure of human SLC15A4 dimer in outward open state in LMNG
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Solute carrier family 15 member 4 | polymer | 577 | 62004.0 | 2 | UniProt (Q8N697) Pfam (PF00854) | Homo sapiens (human) | |
| 2 | C, D, E, G, H... (A, C) | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 12 | Chemie (Y01) | |||
| 3 | F, N (A, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
| 4 | J, R (A, C) | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 751.0 | 2 | Chemie (PGT) |
Sequence modifications
A, C: 1 - 577 (UniProt: Q8N697)
| PDB | External Database | Details |
|---|---|---|
| Ala 14 | Leu 14 | engineered mutation |
| Ala 15 | Leu 15 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 124008.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 7785.2 | |
| All* | Total formula weight | 131793.2 |
