8QSL
Cryo-EM structure of human SLC15A4 dimer in outward open state in LMNG
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, C | Solute carrier family 15 member 4 | polymer | 577 | 62004.0 | 2 | UniProt (Q8N697) Pfam (PF00854) In PDB | Homo sapiens (human) | |
2 | A, C | CHOLESTEROL HEMISUCCINATE | non-polymer | 486.7 | 12 | Chemie (Y01) | |||
3 | A, C | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 2 | Chemie (NAG) | |||
4 | A, C | (1S)-2-{[{[(2R)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL STEARATE | non-polymer | 751.0 | 2 | Chemie (PGT) |
Sequence modifications
A, C: 1 - 577 (UniProt: Q8N697)
PDB | External Database | Details |
---|---|---|
Ala 14 | Leu 14 | engineered mutation |
Ala 15 | Leu 15 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 124008.1 | |
Non-Polymers* | Number of molecules | 16 |
Total formula weight | 7785.2 | |
All* | Total formula weight | 131793.2 |