8QS3
Ternary structure of 14-3-3s, C-RAF phosphopeptide (pS259) and compound 23 (1083848)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, M) | 14-3-3 protein sigma | polymer | 235 | 26485.9 | 2 | UniProt (P31947) Pfam (PF00244) | Homo sapiens (human) | Epithelial cell marker protein 1,Stratifin |
| 2 | B, D (K, Y) | C-RAF peptide pS259 | polymer | 10 | 1208.2 | 2 | Homo sapiens | ||
| 3 | E, K, N, O (A, M) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | F, G, H, I, L... (A, M) | MAGNESIUM ION | non-polymer | 24.3 | 10 | Chemie (MG) | |||
| 5 | J, T (A, M) | 2-chloranyl-~{N}-[[1-(4-iodophenyl)sulfonylpiperidin-4-yl]methyl]ethanamide | non-polymer | 456.7 | 2 | Chemie (WQI) | |||
| 6 | U, V, W, X (A, K, M, Y) | water | water | 18.0 | 446 | Chemie (HOH) |
Sequence modifications
A, M: 1 - 231 (UniProt: P31947)
| PDB | External Database | Details |
|---|---|---|
| Ala -3 | - | expression tag |
| Met -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 55388.1 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1298.3 | |
| All* | Total formula weight | 56686.4 |
