8QP7

Crystal structure of Hepatitis C Virus E2 glycoprotein epitopeI 411-424 scaffold design 4CIL_04

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Yop effector YopM,Internalin B	polymer	296	33068.5	1	UniProt (P74988) UniProt (P0DQD2) Pfam (PF12468) Pfam (PF12799) Pfam (PF08191)	Yersinia enterocolitica	4CIL_04
2	B (A)	water	water		18.0	127	Chemie (HOH)

Sequence modifications

A: 6 - 50 (UniProt: P74988)

PDB	External Database	Details
Met 1	-	initiating methionine
Gly 2	-	expression tag
Ala 3	-	expression tag
Met 4	-	expression tag
Gly 5	-	expression tag
Gly 24	Pro 52	engineered mutation
Ala 40	Cys 68	engineered mutation
Ser 45	Ala 73	engineered mutation

A: 51 - 288 (UniProt: P0DQD2)

PDB	External Database	Details
Leu 53	Ser 86	engineered mutation
Gly 54	Asp 87	engineered mutation
Leu 55	Ile 88	engineered mutation
Ser 56	Lys 89	engineered mutation
Leu 58	Val 91	engineered mutation
Pro 59	Gln 92	engineered mutation
Ile 209	Cys 242	engineered mutation
Asp 228	Asn 261	engineered mutation
Thr 234	Val 267	engineered mutation
Ala 237	Glu 270	engineered mutation
Arg 266	Tyr 299	engineered mutation
Leu 268	Pro 301	engineered mutation
Asn 270	Thr 303	engineered mutation
Gly 273	Lys 306	engineered mutation
Ser 274	Ala 307	engineered mutation
Trp 275	Lys 308	engineered mutation
Ile 277	Arg 310	engineered mutation
Ser 279	His 312	engineered mutation
Gly 289	-	expression tag
Ser 290	-	expression tag
Glu 291	-	expression tag
Asn 292	-	expression tag
Leu 293	-	expression tag
Tyr 294	-	expression tag
Phe 295	-	expression tag
Gln 296	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	33068.5
All*	Total formula weight	33068.5

*Water molecules are not included.