8QOW
LTA4 hydrolase in complex with compound 2(S)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Leukotriene A-4 hydrolase | polymer | 613 | 69444.0 | 1 | UniProt (P09960) Pfam (PF17900) Pfam (PF01433) Pfam (PF09127) | Homo sapiens (human) | LTA-4 hydrolase,Leukotriene A(4) hydrolase |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C (A) | ACETATE ION | non-polymer | 59.0 | 1 | Chemie (ACT) | |||
| 4 | D, E (A) | YTTERBIUM (III) ION | non-polymer | 173.0 | 2 | Chemie (YB) | |||
| 5 | F, G (A) | IMIDAZOLE | non-polymer | 69.1 | 2 | Chemie (IMD) | |||
| 6 | H (A) | (2~{S})-2-azanyl-3-[3-[4-[3-fluoranyl-5-(1~{H}-pyrazol-5-yl)pyridin-2-yl]oxyphenyl]pyrazol-1-yl]propan-1-ol | non-polymer | 394.4 | 1 | Chemie (WID) | |||
| 7 | I (A) | water | water | 18.0 | 450 | Chemie (HOH) |
Sequence modifications
A: 2 - 611 (UniProt: P09960)
| PDB | External Database | Details |
|---|---|---|
| Gly -1 | - | expression tag |
| Pro 0 | - | expression tag |
| Gly 1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 69444.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1003.1 | |
| All* | Total formula weight | 70447.1 |
