8QMT
Succinic semialdehyde dehydrogenase from E. coli with Q262R substitution and bound NAD+, succinic semialdehyde
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Succinate semialdehyde dehydrogenase [NAD(P)+] Sad | polymer | 462 | 49798.8 | 4 | UniProt (P76149) Pfam (PF00171) | Escherichia coli K-12 | SSADH,SSDH |
| 2 | E, G, I, K (A, B, C, D) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 4 | Chemie (NAD) | |||
| 3 | F, H, J, L (A, B, C, D) | 4-oxobutanoic acid | non-polymer | 102.1 | 4 | Chemie (SSN) | |||
| 4 | M, N, O, P (A, B, C, D) | water | water | 18.0 | 1293 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 462 (UniProt: P76149)
| PDB | External Database | Details |
|---|---|---|
| Arg 262 | Gln 262 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 199195.0 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 3062.1 | |
| All* | Total formula weight | 202257.1 |
