8QMT
Succinic semialdehyde dehydrogenase from E. coli with Q262R substitution and bound NAD+, succinic semialdehyde
Functional Information from PROSITE/UniProt
| site_id | PS00070 |
| Number of Residues | 12 |
| Details | ALDEHYDE_DEHYDR_CYS Aldehyde dehydrogenases cysteine active site. YrNTGQVCAAAK |
| Chain | Residue | Details |
| A | TYR261-LYS272 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU10008 |
| Chain | Residue | Details |
| A | GLU234 | |
| B | GLU234 | |
| C | GLU234 | |
| D | GLU234 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU10008 |
| Chain | Residue | Details |
| A | CYS268 | |
| B | CYS268 | |
| C | CYS268 | |
| D | CYS268 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 20 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:P25526 |
| Chain | Residue | Details |
| A | TRP136 | |
| B | GLU365 | |
| C | TRP136 | |
| C | LYS160 | |
| C | GLY212 | |
| C | LEU235 | |
| C | GLU365 | |
| D | TRP136 | |
| D | LYS160 | |
| D | GLY212 | |
| D | LEU235 | |
| A | LYS160 | |
| D | GLU365 | |
| A | GLY212 | |
| A | LEU235 | |
| A | GLU365 | |
| B | TRP136 | |
| B | LYS160 | |
| B | GLY212 | |
| B | LEU235 |
