8QHR
Crystal structure of the human DNPH1 glycosyl-enzyme intermediate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | polymer | 147 | 16337.4 | 2 | UniProt (O43598) Pfam (PF05014) In PDB | Homo sapiens (human) | c-Myc-responsive protein RCL |
| 2 | A, B | 1',2'-DIDEOXYRIBOFURANOSE-5'-PHOSPHATE | non-polymer | 198.1 | 2 | Chemie (3DR) | |||
| 3 | A | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 4 | B | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 282.3 | 1 | Chemie (B3P) | |||
| 5 | water | water | 18.0 | 286 | Chemie (HOH) |
Sequence modifications
A, B: 19 - 162 (UniProt: O43598)
| PDB | External Database | Details |
|---|---|---|
| Gly 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Met 18 | - | expression tag |
| Gln 55 | Glu 55 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 32674.7 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 802.7 | |
| All* | Total formula weight | 33477.4 |
